A Textbook Of Modern Toxicology
Penulis: Hodgson, Ernest
Impresum: NEW YORK: JOHN WILEY & SONS, INC; 2010
Kolasi: xxiv, 648 hlm.
ISBN: 978-0-470-46206-5
A Textbook of Modern Toxicology is a unique resource that provides both students and practitioners with a wide-ranging, accessible overview of the discipline. Suitable for courses in environmental, pharmacological, medical, and veterinary toxicology, this essential text features chapters written by experts who address a range of key topics.
The Fourth Edition includes additional chapters on new approaches to toxicology - molecular methods (-omics: toxicogenomics, proteomics, and metabolomics), bioinformatics, and systems biology – and continues the legacy of its predecessors to provide up-to-date insights into acute toxicity and chemical carcinogenesis, organ toxicity, in vitro and in vivo toxicity testing, ecological risk assessment, and many other areas of toxicology that help foster a solid comprehension of the field.
Also featured in the Fourth Edition are end-of-chapter questions and a Solutions Manual available separately for academic adopters.
keyword: absorption acid activity acute toxicity agents air pollution aldehyde animals antibodies arsenic benzo(a)pyrene binding Biochemical Toxicology blood body cadmium cancer carcinogenic catalyzed cause cells cellular Chapter chemical Chlorpyrifos chronic compounds concentration conjugation contamination cytochrome cytochrome P450 dermal diffusion disease dose drug elimination environmental enzymes epoxide example excretion exposure factors Figure function gene glucuronidation glutathione herbicides Hodgson hormone human hydrocarbons important increase induced inhibition inhibitors insecticides interaction involved ionized isoforms kidney lead levels lipid lipophilic liver lung mechanisms membrane mercury metabolism metabolites metals mg/kg microsomal molecular molecules monooxygenase mutations nervous system occur organisms oxidation particles partition coefficient pesticides pharmacokinetic Phase phenobarbital piperonyl butoxide plasma poisoning potential produce proteins pyrethrins pyrethroids rats reactions reactive intermediates reactive metabolites receptor response result risk skin species studies substrates sulfur tests tissue toxic effects toxicity Toxicology toxins transport tumor vivo xenobiotic metabolism xenobiotics
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